THYROIDISM EFFECT ON ALOPECIA PATIENTS IN PAKISTAN
MUHAMMAD WAQAR MAZHAR *
Department of Bioinformatics and Biotechnology, Government College University, Faisalabad, Pakistan.
TUBA SALEEM
Department of Bioinformatics and Biotechnology, Government College University, Faisalabad, Pakistan.
MUHAMMAD IRFAN
Department of Bioinformatics and Biotechnology, Government College University, Faisalabad, Pakistan.
ABDUL MANAN
Department of Bioinformatics and Biotechnology, Government College University, Faisalabad, Pakistan.
MUDASARA SIKANDAR
Department of Bioinformatics and Biotechnology, Government College University, Faisalabad, Pakistan.
UJALA KHAN
Department of Bioinformatics and Biotechnology, Government College University, Faisalabad, Pakistan.
HIRA IFTIKHAR
Department of Bioinformatics and Biotechnology, Government College University, Faisalabad, Pakistan.
SAIRA SAIF
Department of Bioinformatics and Biotechnology, Government College University, Faisalabad, Pakistan.
JAVERIA MEHMOOD
Department of Bioinformatics and Biotechnology, Government College University, Faisalabad, Pakistan.
MEHVISH MUMTAZ
Center of Applied Molecular Biology (CAMB), University of Punjab, Lahore, Pakistan.
*Author to whom correspondence should be addressed.
Abstract
TSH is a hormone that is secreted by the anterior lobe of the pituitary gland and stimulates the secretions of the thyroid gland. Its secretions are controlled by the TSH-R on the epithelial cells of the thyroid gland. It controls the production of the thyroxin hormone from the thyroid gland that is involved in the production of heat and energy. But the excessive amount of this hormone leads to the hair fall in some of the peoples. Hyperthyroidism correlates with the human skin and hair structure and its function. In the case of hyperthyroidism hair bulb cell proliferation increases and hence hair fall rate also increases. While in the case of hypothyroidism the bulb cell proliferation reduces and so, hair fall increases. Samples from different regions of the south Punjab were taken that were analyzed by the special chemistry analyzer (minividas). The concentrations of the T4, T3, and TSH were measured. Some of the alopecia patients were recorded high-level TSH. The patients were treated with thyroxin tablets that reduce TSH level. After that, the patients are also treated with hair fin tab, folli one shampoo, wistin tab, and multivitamins. Now the patients were observed with a microscope. The growth of hair follicles and hairs was recorded. Hence, the thyroxin tab uses to decrease the TSH level in the body for 1 month. Hair fin tab, folli one shampoo, wistin tab, and multivitamins are the best treatment methods for the growth of hairs in alopecia patients.
Keywords: TSH (thyroid stimulating hormone), TSH-R (thyroid stimulating hormone receptor), FSH (follicle stimulating hormone), LH (Luteinizing hormone)