Asian Journal of Advances in Medical Science

Belladonna is important herbal medicine popular in India. About 100 pregnant female Indian rats were experimented by administrating the extract of Belladonna to study the effect for abortion. Rats showed the different behavior when the different doses were administered in their body by injection. The first cage was used as control while the 2^nd 3^rd 4^th 5^th cages was used as experimental animals inhabited 10 pregnant female in each cage. The control cage were not supplied  any dose while cage 2^nd were supplied 20ppm of Belladonna extract resulted abnormal behavior in all the test animals but the not any abortion or death have been reported. The 3^rd cage was supplied 40ppm of belladonna extract showing abnormal behavior in 80% cases while abortion in 20% cases but no case of death of test animals have been reported. In the 4^th cage 60ppm belladonna extract were supplied showed abnormality in 60% animals, abortion in 40% animals was found and no death is reported. In the 5^th cage 80ppm belladonna abstract was supplied resulted abnormal behavior in 40% animals, abortion in 60% cases and death in 10% test animals. Cage 6^th showed not the abnormal behavior in any test animal but abortion in 100% cases followed by death in 80% animals with abortion. The correlation test have been conducted between the concentration of extract and rate of abortion have been estimated as +0.758256 showing a high  degree of positive correlation as the concentration of extract is increasing the abortion rate also increases. The correlation test also conducted between extract concentration and death rate showed very low positive correlation i.e. +0.123476. The F- Test (Anova) have been conducted to check the significance of data, the F- value have been calculated as 3.92 at 5 degree of freedom and 10% probability less than the tabulated value 4.74 therefore data is significant.