PATHOPHYSIOLOGY, INVESTIGATIONS, AND MANAGEMENT OF VENTRICULAR SEPTAL DEFECT
OMAR ELSAKA *
Mansoura Manchester Medical Program (MMMP) , Department of Cardiology, Mansoura University, Faculty of Medicine, Mansoura, Egypt.
MOSTAFA TAREK GHAZALI
Mansoura Manchester Medical Program (MMMP) , Department of Cardiology, Mansoura University, Faculty of Medicine, Mansoura, Egypt.
ASHRAF HAMADA ABD AL-RAZIK
Mansoura Manchester Medical Program (MMMP) , Department of Cardiology, Mansoura University, Faculty of Medicine, Mansoura, Egypt.
DALIA HISHAM
Mansoura Manchester Medical Program (MMMP) , Department of Cardiology, Mansoura University, Faculty of Medicine, Mansoura, Egypt.
ABDULSALAM MAHMOUD ALGAMAL
Mansoura Manchester Medical Program (MMMP) , Department of Cardiology, Mansoura University, Faculty of Medicine, Mansoura, Egypt.
*Author to whom correspondence should be addressed.
Abstract
Background: Ventricular septal defects (VSDs) are still one of the most prevalent surgical indications in newborns and children with congenital heart disease. With advances in echocardiography, cardiac catheterization is no longer necessary in the treatment of these individuals. Although perioperative mortality and morbidity for isolated defects are still low, unique scenarios such as surgical care of numerous VSDs and decision-making in patients with pulmonary hypertension remain difficult. This chapter examines both classic and recent evidence that has shaped the management of this condition, as well as the facts underlying developing interventional methods utilized in both the catheterization lab and the operating room.
Conclusion: VSD is the most common congenital abnormality at birth. Small flaws should close on their own within the first year of life; however, larger faults can cause serious difficulties. The major interventions for big problems are surgical VSD closure and device closure.
Keywords: Ventricular septal defect, echocardiography, surgical closure, percutaneous treatment
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Voitov A, Omelchenko A, Gorbatykh Y, et al. Outcomes of perventricular off-pump versus conventional closure of ventricular septal defects: a prospective randomized study. Eur J Cardiothorac Surg. 2017 May 1. 51 (5):980-6.
Fu YC, Bass J, Amin Z, et al. Transcatheter closure of perimembranous ventricular septal defects using the new Amplatzer membranous VSD occluder: results of the U.S. phase I trial. J Am Coll Cardiol. 2006 Jan 17. 47(2):319-25.
Yip WC, Zimmerman F, Hijazi ZM. Heart block and empirical therapy after transcatheter closure of perimembranous ventricular septal defect. Catheter Cardiovasc Interv. 2005 Nov. 66(3):436-41.
Predescu D, Chaturvedi RR, Friedberg MK, Benson LN, Ozawa A, Lee KJ. Complete heart block associated with device closure of perimembranous ventricular septal defects. J Thorac Cardiovasc Surg. 2008 Nov. 136(5):1223-8.
Szkutnik M, Kusa J, Bialkowski J. Percutaneous closure of perimembranous ventricular septal defects with Amplatzer occluders--a single centre experience. Kardiol Pol. 2008 Sep. 66(9):941-7.
Ghosh S, Sridhar A, Solomon N, Sivaprakasham M. Transcatheter closure of ventricular septal defect in aortic valve prolapse and aortic regurgitation. Indian Heart J. 2018 Jul - Aug;70(4):528-532.
Hopkins MK, Goldstein SA, Ward CC, Kuller JA. Evaluation and Management of Maternal Congenital Heart Disease: A Review. Obstet Gynecol Surv. 2018 Feb;73(2):116-124.
Kenny D. Interventional Cardiology for Congenital Heart Disease. Korean Circ J. 2018 May;48(5):350-364.
Ammash NM, Warnes CA. Ventricular septal defects in adults. Ann Intern Med. 2001 Nov 06;135(9):812-24.
Muthialu N, Balakrishnan S, Sundar R. Single patch closure of multiple VSDs through right atrial approach. Indian Heart J. 2018 Jul - Aug;70(4):578-579.
Durden RE, Turek JW, Reinking BE, Bansal M. Acquired ventricular septal defect due to infective endocarditis. Ann Pediatr Cardiol. 2018 Jan-Apr;11(1):100-102.
Patel ND, Kim RW, Pornrattanarungsi S, Wong PC. Morphology of intramural ventricular septal defects: Clinical imaging and autopsy correlation. Ann Pediatr Cardiol. 2018 Sep-Dec;11(3):308-311.
Maagaard M, Heiberg J, Eckerström F, Asschenfeldt B, Rex CE, Ringgaard S, Hjortdal VE. Biventricular morphology in adults born with a ventricular septal defect. Cardiol Young. 2018 Dec;28(12):1379-1385.
Hadeed K, Hascoët S, Karsenty C, Ratsimandresy M, Dulac Y, Chausseray G, Alacoque X, Fraisse A, Acar P. Usefulness of echocardiographic-fluoroscopic fusion imaging in children with congenital heart disease. Arch Cardiovasc Dis. 2018 Jun - Jul;111(6-7):399-410.
Garg N, Nayyar M, Khouzam RN, Salem SA, Ardeshna D. Peri-procedural antibiotic prophylaxis in ventricular septal defect: a case study to re-visit guidelines. Ann Transl Med. 2018 Jan;6(1):18.
Cresti A, Giordano R, Koestenberger M, Spadoni I, Scalese M, Limbruno U, Falorini S, Stefanelli S, Picchi A, De Sensi F, Malandrino A, Cantinotti M. Incidence and natural history of neonatal isolated ventricular septal defects: Do we know everything? A 6-year single-center Italian experience follow-up. Congenit Heart Dis. 2018 Jan;13(1):105-112.
Cantinotti M, Assanta N, Murzi B, Lopez L. Controversies in the definition and management of insignificant left-to-right shunts. Heart. 2014 Feb;100(3):200-5.
Goldberg JF. Long-term Follow-up of "Simple" Lesions--Atrial Septal Defect, Ventricular Septal Defect, and Coarctation of the Aorta. Congenit Heart Dis. 2015 Sep-Oct;10(5):466-74.
Hoashi T, Yazaki S, Kagisaki K, Kitano M, Shimada M, Shiraishi I, Ichikawa H. Importance of multidisciplinary management for pulmonary atresia, ventricular septal defect, major aorto-pulmonary collateral arteries and completely absent central pulmonary arteries. Gen Thorac Cardiovasc Surg. 2017 Jun;65(6):337-342.
Schuh M, Schendel S, Islam S, Klassen K, Morrison L, Rankin KN, Robert C, Mackie AS. Parent readiness for discharge from a tertiary care pediatric cardiology unit. J Spec Pediatr Nurs. 2016 Jul;21(3):139-46.
Wood P. The Eisenmenger syndrome or pulmonary hypertension with reversed central shunt. Br Med J. 1958 Sep 27. 2(5099):755-62.
Van Praagh R, Geva T, Kreutzer J. Ventricular septal defects: how shall we describe, name and classify them?. J Am Coll Cardiol. 1989 Nov 1. 14(5):1298-9.
Wu MH, Wu JM, Chang CI, et al. Implication of aneurysmal transformation in isolated perimembranous ventricular septal defect. Am J Cardiol. 1993 Sep 1. 72(7):596-601.
Wu MH, Wang JK, Lin MT, et al. Ventricular septal defect with secondary left ventricular-to-right atrial shunt is associated with a higher risk for infective endocarditis and a lower late chance of closure. Pediatrics. 2006 Feb. 117(2):e262-7.
Rubin JD, Ferencz C, Loffredo C. Use of prescription and non-prescription drugs in pregnancy. The Baltimore- Washington Infant Study Group. J Clin Epidemiol. 1993 Jun. 46(6): 581-9.