Asian Journal of Advances in Medical Science

The Siddha system of medicine, rooted in ancient Tamil traditions, provides a holistic approach to health encompassing prevention, treatment, and rejuvenation. Among its classical formulations, Pavanak Katukkay, described in Agathiyar Vaithiya Sinthamani 4000, has long been used in the management of nasal ailments such as Nasikapeedam (nasal polyps). This review explores the botanical identity, phytochemistry, and pharmacological activities of its herbal and mineral ingredients, drawing evidence from Siddha texts and modern scientific databases. Findings indicate that Pavanak Katukkay possesses promising anti-inflammatory, mucolytic, antimicrobial, and immunomodulatory properties relevant to the pathophysiology of nasal polyps. While these insights highlight its potential therapeutic value and role in integrative medicine, the absence of clinical trials on the complete formulation remains a critical gap. Future systematic research, including pharmacokinetic profiling and randomized controlled studies, is essential to establish its safety, efficacy, and clinical applicability.